Characterization of patients with diabetic kidney disease non-albuminuric phenotype.

A single-center observational study.

Abstract

Introduction: The phenotypes with albuminuria and the non-albuminuric phenotype in diabetic kidney disease (DKD) are known. The non-albuminuric phenotype is defined with an estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m2 associated with an albuminuria-creatinuria ratio (ACR) less than 30 mg/gr. The objective of the present study was to describe the clinical characteristics of patients with ERD non-albuminuric phenotype (ERDnA).

Methods: This is an observational, descriptive study of patients treated at an IPS in Cartagena, Colombia, from 2021 to 2022.

Results: Of a total of 7698 patients with ERD criteria, 1714 patients (22.3%) had ERDnA criteria, with a median age of 69 years (IQR 62-76), and women (75.73%). A total of 85% had HTN (22.3%) dyslipidemia, and the average BMI was in the overweight range. 9.5% had a history of smoking. Little presence of diabetic retinopathy was found.

Conclusion: Non-albuminuric phenotype diabetic kidney disease (RDnA) is not so uncommon in our environment. In general, the characteristics of our patients are very similar to the data reported in other series.