Acute kidney failure and sepsis in cancer patients.

Narrative review.

Authors

DOI:

https://doi.org/10.56867/66

Keywords:

Acute kidney injury, Sepsis

Abstract

Introduction: The precise incidence of acute kidney injury (AKI) in the population oncology remains unknown; however, the impact is strong on morbidity and mortality 
and in hospitalization costs. Sepsis and hypoperfusion are very common etiologies 
of AKI in cancer patients converge on pre-renal and intrinsic causes.

Objective of the review: The review aims to describe the main aspects of pathophysiological and establish diagnostic and treatment criteria in patients with Acute kidney injury and sepsis in cancer patients.

Essential points of the review: A significant group of cancer patients 
With immunosuppressants, they develop viral infections with sepsis and acute kidney failure. Although the 
AKI in patients with sepsis is multifactorial; the primary mechanism is tubular necrosis acute after renal hypoperfusion due to circulatory failure. The early administration of Antibiotics and control of the etiological basis of sepsis are usually the pillars of prevention.

Conclusion: The prognosis of ICU patients with severe sepsis-related ARF is poor, reaching an in-hospital mortality rate of 70%. Furthermore, the presence of leukemia or lymphoma is an independent predictor of mortality in the ICU. Unfortunately, no agent has proven effective in preventing severe sepsis.

Published

2024-02-24

How to Cite

Acute kidney failure and sepsis in cancer patients.: Narrative review. (2024). Revista De La Sociedad Ecuatoriana De Nefrología, Diálisis Y Trasplante, 12(1), 1-8. https://doi.org/10.56867/66

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